Submitting genomic data to public repositories is essential for open science, but it can also be a time-consuming and technically demanding process. To make this easier, ELIXIR Belgium/VIB Data Core has developed a streamlined workflow for submitting raw sequencing reads and genome assemblies to the European Nucleotide Archive (ENA).
 

The workflow was created in the context of the EU-funded EVORA project and is now openly accessible to researchers across Europe. Its goal: lowering the barriers for making genomic datasets FAIR, reusable, and compliant with ENA requirements.
 

What the workflow does

The ENA submission workflow, fully integrated into the useGalaxy environment, walks researchers through every step of a complete submission:

1. Metadata preparation using standardized, ENA-ready templates
2. File and metadata validation to ensure compliance before submission
3. Automated submission of raw reads and genome assemblies
4. Comprehensive logging and tracking, supporting reproducibility and audit needs
    

Designed with usability in mind, the workflow is suited for both beginners and experienced bioinformaticians. It supports single-submission projects as well as large batch submissions, and connects seamlessly with existing Galaxy datasets and tools.

Are you preparing raw reads or assemblies for ENA?

Try the workflow today via WorkflowHub or directly on useGalaxy.be, and make your submissions faster, cleaner, and fully compliant. For support, reach out to ELIXIR Belgium or explore the documentation available with the workflow.