Proteins perform a wide variety of functions in cells through interactions with each other and many additional molecules. These interactions are traditionally understood from a static description (a picture); however proteins are not static, on the contrary they change between multiple states (a movie). They move dynamically between these states (conformations) - my research is aimed elucidating the relation between dynamics, conformation and experimental (mostly NMR) data on proteins. By unravelling the underlying physical and chemical principles with statistics and informatics, and relating them to biological events, we try to better understand how proteins work, and generate new approaches that predict how they work - placing the research in the interdisciplinary structural bioinformatics or structural computational biology category. Director of the Interuniversity Institute of Bioinformatics in Brussels (IB)2.
Office: Room E 5.05, Pleinlaan 2, 1050 Brussel, Belgium
Office Phone: +32(0)2 629 19 96
Lab: Structural Biology Brussels, Free University of Brussels